Skip to main content
    Thrive On

    Give your in-center patients the hope for a more active, longer life

    HDF is a breakthrough treatment combining diffusion and convection processes to elevate the standard of in-center care. Utilizing advanced technology to remove more molecules—including middle molecule uremic toxins—HDF has the potential to improve patients' quality of life.

    HDF combines diffusion (hemodialysis - HD) with convection (hemofiltration - HF) to remove middle molecules more efficiently. The advanced process leads to better clearance of toxins, waste, and excess fluid, leaving patients with cleaner blood, and in many cases, feeling better—right after treatment and beyond. The increased removal of toxins also helps to reduce inflammation and cardiovascular complications, supporting better clinical outcomes.

    How HDF works
    Up Arrow
    Longer life1
    Studies show HDF can improve survival by 23% when treatment is done at high volume (≥23L), which removes more toxins and fluid to decrease strain on the heart.
    Down Arrow
    Fewer hospitalizations2
    The proprietary prescribing algorithm for HDF treatment developed by Fresenius Medical Care helps patients achieve less intradialytic hypotension2, less inflammation and fewer complications.3
    Person Walking
    Greater quality of life1
    In-center hemodiafiltration helps patients feel better after dialysis and between treatments. Improved energy levels encourage improved social participation, activity, and adherence.1

    How HDF supports improved clinical outcomes

    HDF utilizes a high-flux dialyzer, a new machine, and online fluid replacement to individualize the delivery of care. This advanced process can remove more middle molecules, including uremic toxins, for lower incidents of hypotension, less inflammation, and better preservation of albumin.

    Middle molecule removal, hd vs. hdf
    Watch a video about HDF
    “This is going to be a game changer in terms of affecting patients' overall health and longevity”

    — Dr. Siddharth Bhatt, MD
    Nephrologist

    Watch video
    Support to educate your patients on HDF treatment
    We're here for your patients throughout their treatment journey. Our care teams support the transition from HD to HDF treatment with education, empathy, and helpful answers to questions.

    • Engaging patients with the potential treatment benefits
    • Supporting their understanding of the hemodiafiltration process
    • Guiding patients through expectations as they transition from HD to HDF
    Watch a video about Eduardo's story
    “When I wasn't on it, I got home and would just fall asleep. But now, I get home, I eat, and I feel good.”

    — Eduardo, On HDF

    Watch his story
    Hemodialysis partner.

    Help your in-center patients get the full benefits of HDF

    As with conventional HD, it's essential for patients to complete their full treatment as prescribed to feel their best. Most patients are able to achieve the necessary HDF convective clearance with a 4-hour treatment, 3 days per week. Potential reduction in dialysis complications and improvement in energy and overall feeling of well-being on HDF are expected to support adherence to treatment time.

    Thumbs up
    HDF may help your patients feel better, so they may notice:
    • Longer life
    • More energy
    • Better sleep
    • Less mental decline
    • Less recovery time after treatment
    • Improved overall health
    Hemodialysis partner.

    Prepare to start patients on HDF

    As HDF comes to your market, help your patients transition so they can feel their best. Our algorithm can support you with prescribing HDF during the transition from HD.

    Questions? Contact your Market Development Representative or email us.

    References:
    1. CONVINCE study: Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure. The New England Journal of Medicine. Blankestijn et al. June 16, 2023. Comparison of high-dose HDF with high-flux HD in European patients. 2. Maduell et al. JASN (2013) 24(3):487-97. 3. Panichi et al. Nephrol Dial Transplant (2008) 23: 2337-43. 4. Advancing and Personalizing Kidney Disease Care: 2024 Annual Medical Report. Strategy to Expand High-Volume Hemodiafiltration Worldwide. Stefano Stuard, MD, PhD and Michael S. Anger, MD, FACP, FASN.

    For patients wanting to know more about HDF at Fresenius Kidney Care
    Learn more
    “I try it, and I see in a couple weeks that I feel better. I'm at my best.”
    — Nikolaos
    On HDF
    Watch his story
    “He tells me that he feels the best he's felt and that he's finally been sleeping better.”
    — Danielle Tressler, RN, CDN
    Clinical Manager,
    Fresenius Kidney Care
    HDF Kick-off Series
    We will be hosting kick-off meetings in select markets for those who are local (Worcester, MA, Somerville, MA, St. Paul, MN, Covington, LA, and Kennesaw, GA). Keep up with our latest events.
    Register now
    Patient resources
    Fresenius Kidney Care offers patient education to help you and our care teams educate people on dialysis. Check out our patient education content.
    Learn more